C19 Notes

General Category => C19 Notes Database => Topic started by: stog on May 17, 2020, 09:56:47 AM

Title: Vaccinated llama produced nanobodies that could neutralize coronavirus
Post by: stog on May 17, 2020, 09:56:47 AM
Llamas like Winter are well suited to this kind of research because they produce nanobodies: about half the size of the antibodies a human would make, that occur in sharks and camelids (such as llamas, alpacas and camels).

Quote
"That reduced size makes them potentially really interesting therapeutic candidates because they can wedge themselves into little crevices that our larger antibodies wouldn't otherwise be able to access," said Wrapp.


https://www.cbc.ca/radio/thecurrent/the-current-for-may-11-2020-1.5564274/meet-winter-the-4-year-old-llama-whose-blood-might-hold-a-treatment-for-covid-19-1.5564528

 (https://www.cbc.ca/radio/thecurrent/the-current-for-may-11-2020-1.5564274/meet-winter-the-4-year-old-llama-whose-blood-might-hold-a-treatment-for-covid-19-1.5564528)

The findings were published last week in the scientific journal Cell, in collaboration with researchers at Ghent University in Belgium.

pdf here (https://www.cell.com/cell/pdf/S0092-8674(20)30494-3.pdf)